Clean the surface of the shoe with a damp rag, wiping away any dirt.
Spray the Nike Air shoes with shoe cleaner or a mild detergent mixed with water.
Wet an old toothbrush and use it to scrub the dirt out of the cracks and crevices of the shoe, including around the air bubble.
Wipe the surface of the shoe with a clean damp cloth to remove the dirt. You can rinse them under a faucet first if they are very dirty. Be careful not to get water inside the shoe.
Dry off the shoes with a towel and allow them to finish air drying before wearing.